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Population-level effect of HIV on adult mortality and early evidence of reversal after introduction of antiretroviral therapy in Malawi

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English: Web Page


The effect of HIV infection on the mortality rates of male and females in sub-Saharan Africa is devastating. HIV associated mortality, in the age range of 15 to 59 years, represents 59% of the total mortality in Malawi. (Egger, 2008) At such high rates of infection and death, some have argued that the epidemic cannot be reversed in the near future. Many of these dire predictions did not account for the rapid scale up of ART. This report by Jahn and associates describes the implementation of ART over a two-year period from 2004 to 2006 and provides evidence of a significant impact on mortality in the overall population. Similar studies have been reported from South Africa. (Barnighausen et al., 2008) In addition to the goal of providing ART to improve life expectancy of individuals, this study demonstrates a broad population effect of ART, suggesting that the rapid deployment of ARVs could overcome the effect of the loss of large numbers of individuals on the social, economic and political infrastructure of communities and countries.

Related Resources

Publisher: Elsevier
Language: English
Format: Web Page
Regions: Sub-Saharan Africa, Malawi
Audiences: Doctors/Physicians, Policymakers, Program Managers, Researchers
Literacy level: High
Topic Areas: Monitoring and Evaluation , Antiretroviral Treatment & Complications
Resource Type: Journal Articles