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Antiretroviral therapy (ART) for treating HIV infection in ART-eligible pregnant women

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English: Web Page

Summary

This systematic review focuses on antiretroviral therapy (ART) for treating human immunodeficiency virus (HIV) infection in ART-eligible pregnant women. Mother-to-child transmission (MTCT) is the primary means by which children worldwide acquire HIV infection. MTCT occurs during three major timepoints during pregnancy and the postpartum period: in utero, intrapartum, and during breastfeeding. Strategies to reduce MTCT focus on these periods of exposure and include maternal and infant use of ART, caesarean section before onset of labour or rupture of membranes, and complete avoidance of breastfeeding. Where these combined interventions are available, the risk of MTCT is as low as 1-2%. Thus, ART used among mothers who require treatment of HIV for their own health also plays a significant role in decreasing MTCT.

Publisher: The Cochrane Collaboration
Language: English
Format: Web Page
Region: Global
Audiences: Doctors/Physicians, Policymakers
Topic Areas: Antiretroviral Treatment & Complications, Perinatal Interventions
Resource Type: Research Summaries and Reviews