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Antiretroviral Therapy for HIV Infection in Adults and Adolescents in Resource-limited Settings: Towards Universal Access--Recommendations for a Public Health Approach

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English: PDF [1.76MB]


This publication provides consensus recommendations for HIV treatment for adults and adolescents, taking into account current research on the initiate ART, optimal ART regimens, the management of HIV coinfection with tuberculosis and chronic viral hepatitis and the management of ART failure. These guidelines encourage earlier HIV diagnosis and earlier antiretroviral treatment, and promote the use of the least toxic regimens and strategic laboratory monitoring. The guidelines identify the most potent, effective and feasible first-line, second-line and subsequent treatment regimens, applicable to the majority of populations, the optimal timing of ART initiation and improved criteria for ART switching, and introduce the concept of third-line antiretroviral regimens. The primary audiences are national treatment advisory boards, partners implementing HIV care and treatment, and organizations providing technical and financial support to HIV care and treatment programmes in resource-limited settings.

Related Resources

Publisher: World Health Organization
Language: English
Format: PDF
Region: Global
Audiences: Program Managers, Doctors/Physicians, Nurses, Physician's Assistants/Nurse Practitioners, Trainers
Literacy level: Medium
Topic Area: Antiretroviral Treatment & Complications
Resource Type: Clinical Guidelines